Top similar games like Bioguard:
Bioguard $2.99
Bioguard is a tower defense roguelite with a biological theme. Help the immune system using a variety of towers, skills and special cards. Develop your strategy to protect your body from invading pathogens and prevent their passage to vital organs!
Filters
Price (USD)
Release Date
Recommendations
Retirement Home Tower Defense$6.99
Step into Retirement Home chaos in this comedic tower defense game. The "Old Folks" have stopped taking their meds, wage war against the onslaught of doctors and stop them reaching the medicine cabinet and putting you all down for an afternoon nap.
Bitesize Heroes: Forest Defender$3.99
Prepare for an epic battle in this captivating tower defense game! Build, defend, and triumph as you strategically place towers, manage resources, and upgrade your arsenal to fend off relentless waves of enemies.
Farm for your Life$9.99
Your community was taken down by a heavy storm which caused an apocalypse and unleashed the living dead. Together with the other survivors, it is your task to rebuild and to allow that sustainable life can still be assured. Cultivate your farm and manage your restaurant to provide food and deal with all the zombies.
Purrfect Alchemy$4.99
Purrfect Alchemy is a "purrfect" blend of twin stick shooter, wave survival, tower defender. Craft defenses at the center cauldron with a variety of ingredients you may find. Upgrade spells, defeat bosses and reach the end with up to 3 other friends in this Co-Op adventure
Crush Link TDFREE
A Tower Defense game with new mechanics in virtual setting about online dating. Your task is to protect your base preventing spam from getting into your inbox. Build towers in marked places to stop spam.
Sleep Attack$6.99
Enjoy an amazing new TWIST in Tower Defense! You control the layout of the battlefield, and you decide the paths your enemies follow!
Car Wash TD - Tower Defense$9.99
A simple one-of-a-kind tower defense game where you need to wash cars before they reach the end of the road. Create mazes. Upgrade your towers. Wash all sorts of cars, trucks, boats, and planes.
Kingdom Rush Origins - Tower Defense$14.99
Command your elven army and defend mystical lands from sea serpents, evil sorcerers, and wave after wave of gnoll tribesman, all with the help of brand-spankin’ new towers, heroes, and spells to fend off every last baddie.
Tower Defense: Defender of the Kingdom$2.99
Defender of the Kingdom: Tower Defense is a colorful medieval tower defense strategy game where orcs and their horde attacked the kingdom and now the fate of the kingdom is in your hands, defenders!
Dwarven Skykeep$19.99
A unique blend of base- and deckbuilding wrapped in a medieval fantasy universe and humorous plot. Build and defend your towers using magical cards. Win artifacts to obtain immense power. Complete challenges, adapt to RNG and conditions of five worlds to become a master wizard!
Broken Universe - Tower Defense$9.99
Get ready to rethink all your defense strategies! Build barricades to stop monsters, or lure them into a maze and attack. A variety of stages that change each time depending on how you play them.
Cyndefense 2FREE
Cyndefense 2 is a well crafted, hardcore, tower defense game. While there are easier modes for those who want casual game-play, the game will test your ability to manage your resources and rely on superb tower placement in order to be capable of beating harder maps.
Eternal Elements$9.99
Melt sand, shatter glass, and rust iron in this epic elemental tower defense game. Combine elemental effects to beat powerful materials. Use cunning strategy and wit to take on impossible challenges. Unlock new abilities and power as you embark on this difficult journey.
Defend Your Life: TD$9.99
Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy.
BeeFense BeeMastered$9.99
The bees are back… bigger, bolder, better! Protect your beehive fortress against the hornet menace. After all, the best offense is a good BeeFense! Command your forces, manage your resources, and improve your defenses in increasingly challenging battles.
Color Tower DefenceFREE
All kinds of enemies entered the battlefield! Build your defenses against hordes of enemies!
Beware Planet Earth$4.99
Beware Planet Earth! is a beguiling mix of classic tower defense and time management coming to PC via Steam for the first time. Save your cows from the Martian invasion by building an effective defense using towers, traps and objects, and also by firing your Zapper directly at the invading force of little green men!
The Territory of Egg$2.99
The Territory of Egg is a unique twist on tower defense game. You need to build defense lines with egg warriors to protect the Holy Egg, the core of all eggs. Remember to upgrade your Tech Tree with the resources you've collected and unlock more skills to fight against the evil monsters.
Idle Monster TDFREE
An endless Tower Defense game of epic Monsters vs evil War Machines. Unlock and upgrade tons of unique elemental Monsters (Water, Air, Earth, and Fire) to defend your home from an infinite swarm of robots. Strategize the most effective placement of Monsters to synergize their elemental abilities.
Eye of the Void: Unleashed - Tower Defense$2.99
The goblin tribes of the realm have united against you and the power of the Eye of the Void. Build towers, fortify walls, construct gold mines to gather resources, and cast powerful spells to fend off waves of determined goblins and their allies who seek to destroy you.
Dofense$12.99
Defend the energy cores from ever increasing enemy waves by destroying their spawn gates. Build tower mazes on Hex grid. Adapt them to dynamic changes in the terrain. Face quirky bosses. Design your own levels and share them on the Steam Workshop.
Defend from Candyland!$7.99
Step into the world of Defend from Candyland! where retro tower defense meets strategic depth. Plant and upgrade trees, use powerful buffs, and reveal enemy paths to shield Eden from waves of candy invaders. Master the challenge now!
Bad Mechanic$4.99
Bad Mechanic is a whimsical tower-defense bullet-hell roguelike. Plan (and improvise) your defenses against a swarm of mini middle managers. Dodge your own towers’ attacks as you collect loot. Build a unique arsenal of towers and items in each run that will kill you in spectacular fashion.
Dungeon Warfare$9.99
Dungeon Warfare is a challenging tower defense strategy game where you become a dungeon lord to defend your dungeons with deadliest of traps and insidious contraptions against greedy adventurers and wanna-be heroes.
Ant Attack$0.99
Ant Attack - A peculiar blend of Clicker and Tower Defense.
Mechanical Trap$5.99
Mechanical Trap is a 2D horizontal tower defense game with gravity effects, with a variety of defense towers to collect and use together, a rich map, each enemy has a different way of restraining, and each defense tower has a different function.It's challenging. Do you dare to accept the challenge?
Laser Defense Extreme$1.99
Laser Defense Extreme is a Tower Defense Game, with a Killstreak System. Place your "Towers" strategically and eliminate the incoming enemies.
Botanical TD$3.99
Defend against evil snails with a variety of plants in this Tower Defense while YOU have to make constant decisions how your enemies get stronger.
Defend the Cake$9.99
Defend the Cake is a deliciously strategic tower defense game. Take your time planning a maze of toast walls and delicious defenses. Then get ready to tactically power-up your defenses in real-time and fend off the invading armies of bugs.
主动防御(Active Defense)$0.99
This is a strategy tower defense game where players need to choose the appropriate defense towers based on different maps and enemies. The game also offers a variety of defense towers, maps, and an endless mode waiting to be unlocked by the players!
Mechanines Tower Defense$6.99
Position your EvoDogs against the threats of a machine-dominated future and enjoy this TOWER DEFENSE game with ROGUE-LITE elements!
Bit Tower$1.99
Bit Tower is a simple Tower Defense game where you defend your castle while trying to withstand increasingly larger waves. Hire adventurers, position them strategically, and fight against the waves of monsters.
KannaSchool$9.99
『神奈学園』へようこそ！非常に面白くて革新的な横スクロールタワーディフェンスゲームです！
Tomb Of AnuBI0S$9.99
Tomb of AnuBI0S is an unique 2D tower defense-platformer with an Egyptian Sci-fi setting. Defend the AI deity RAm from waves of undead "Organics." Upgrade your arsenal from weapons to walls, turrets, and your player capabilities. Immerse yourself in meticulously crafted levels and defend RAm!
Mushroom Wars$9.99
Mushroom Wars is a dynamic real-time strategy game, where smart strategy meets furious action in epic PvP and PvE battles.
Do I smell Pizza?$4.99
Chubs ordered some pizza and he DOESN'T SHARE FOOD! Problem is: the smell attracted his hungry family and some speedy rats. To protect the pizza Chubboy will need to install towers of healthy food and spit the rats away in this foody hell shooter tower defence.
Monkey PartyFREE
Merge balls, unleash adorable monkeys, and build a tower of fun in Monkey Party! Master precision placement for maximum monkey mischief. It's a charming puzzle adventure that's easy to play and hard to put down!
史莱姆冒险战SlimeWarfare$5.99
"Slime Warfare" is a rogue tower defense game with a variety of gameplay and placement.Slimes are weak monsters and always bullied by humans. Players will play the role of the Slime Queen to build structures to defend against adventurers' attacks and strengthen themselves.
I Am The Registered Environmental Engineer$6.99
This world is plagued by pollution, and as an engineer, you need to plan waste routes, gather, sort, and transport it to safe areas. Use powerful equipment to finally clean it up and restore cleanliness to the world.
PLANTOONS$1.99
Powerful plants fight off invading weeds in a wacky 2D tower-defense game with Roguelite elements!Build your defenses, upgrade your abilities, complete challenges... and survive the onslaught!
dusk shrouded$7.99
Sandbox game Free content updates
Countless Army$9.99
Be the villain in this Reverse Tower Defense. Send waves after waves of troops to break the enemy defenses. Summon, upgrade your troops and conquer the whole world.
Коты Воители$9.99
Cats Warriors is a strategy game made in 2D hand-drawn graphics with cute cats.
Lord Clicker$2.99
Lord Clicker combines Clicker and Tower Defense in one game. Click to accumulate gold coins and make your choice: buy populace to generate wealth on your behalf, or hire men to defend your village.
Museum No.9$9.99
Massive artifact collection! Build your museum with extreme freedom! Visitor revenue depends on your route design, and whether you can achieve perfect profits is entirely up to you! Enjoy light rogue-style adventure exploration, and use different skill combinations to battle monsters every time!
Firework WarFREE
Use a variety of fireworks to fend off misfortune and protect your family!
Junkyard WarFREE
Junkyard War is a unique take on the tower defense genre. Clear trash from the junkyard and recycle it into valuable resources while holding off waves of your competitor's army trying to make the trash disappear by burning it all down!
Survive In Strange World$4.99
Action adventure strategy game with tower defense, in a fantasy world, use your own combat skills, weapons, and the power of your partners to survive. Face the ultimate fate with your unique combat style.
Summoner Apprentice$1.99
Delve into the mystical art of summoning alongside Feylin, the last of the Ancients. Begin your journey as her new apprentice and learn how to summon minions, outwit your enemies, collect relics to enhance your powers and overcome the dreadful obstacles set in your path.
Special squad versus zombies$9.99
A strange toxin has entered the city and almost all people in the city were transformed into the zombies. The zombies are very ferocious and they can destroy everything that prevents them. There is only one change to save the city, it is the Special Squad.
Kingdom Rush 5: Alliance TD$19.99
While a formidable evil emerges, an unexpected alliance is taking shape! It will take the finest warriors of Linirea and the relentless Dark Army to stop it. Beware! Though they may journey side by side the ever-changing winds of fate could swiftly alter their course.