Top similar games like Defend Your Life: TD:
Defend Your Life: TD $9.99
Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy.
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Retirement Home Tower Defense$6.99
Step into Retirement Home chaos in this comedic tower defense game. The "Old Folks" have stopped taking their meds, wage war against the onslaught of doctors and stop them reaching the medicine cabinet and putting you all down for an afternoon nap.

Touhou Monster TD ~ 幻想乡妖怪塔防$18.99
Easy to learn but hard to master, Touhou Monster TD is a unique Tower defense Game. Control your character, level up and unlock tower skills and character talents, use your wisdom to defeat incoming enemies. Travel the Gensokyo, find out why the “Incident” happened this time.

Towers Together: BeginningsFREE
Towers together is a cooperative tower defense game with cards. Combine your cards with your friends’ cards to achieve powerful combo, but get ready to fail and laugh together. Build towers, cast spells, have fun with friends!

Creator-initial$9.99
A real -time strategy game that can create items to operate logic.No resource collection

Bloons TD Battles 2FREE
From the creators of Bloons TD6... Bloons TD Battles 2 is a brand new installment of the top-rated head-to-head tower defense game. Gather your Hero, choose your team of powerful Monkey Towers, and prepare to battle one on one against other players and relentless waves of Bloons!

dusk shrouded$7.99
Sandbox game Free content updates

Bioguard$2.99
Bioguard is a tower defense roguelite with a biological theme. Help the immune system using a variety of towers, skills and special cards. Develop your strategy to protect your body from invading pathogens and prevent their passage to vital organs!

Do I smell Pizza?$4.99
Chubs ordered some pizza and he DOESN'T SHARE FOOD! Problem is: the smell attracted his hungry family and some speedy rats. To protect the pizza Chubboy will need to install towers of healthy food and spit the rats away in this foody hell shooter tower defence.

Buildy Stacky 2$3.99
Construct towering structures with unconventional building segments, stabilize, detonate, shrink, grow, and stick segments with special powers, all while navigating increasingly difficult challenges in this wacky and brain-teasing game that will delight players of all ages and skill levels.

Just Desserts$4.99
Select your commander and play a series of tower defense levels as you progress through a randomly generated map. Find shops to unlock upgrades for your towers and commander, and fight mini bosses for bonus rewards to prepare for Count Cakeula.

Candy Disaster - Tower Defense$13.99
Candy Disaster is 3D trap-style tower defense game where you guard candies against alien thieves! Unlock powerful and clever traps, choose your arsenal for different bases, and find the deadliest trap combination - then watch those space goons walk into their death!

Botanical TD$3.99
Defend against evil snails with a variety of plants in this Tower Defense while YOU have to make constant decisions how your enemies get stronger.

Small People Defense$4.99
Use projectile-based towers, unique tower interactions, and overpowered weapons to strategically conquer the endless waves in this 3rd-person tower defense game!

Tower Defense: Defender of the Kingdom$2.99
Defender of the Kingdom: Tower Defense is a colorful medieval tower defense strategy game where orcs and their horde attacked the kingdom and now the fate of the kingdom is in your hands, defenders!

ARC Alien Raid Combat$0.99
A game based on the classic Tower Defense style, assemble your best combination to overcome obstacles, can you do it?

Defenders Glory$9.99
Defenders Glory is a Fantasy Tower Defense game with simple but deep gameplay elements: Simple mechanics that allow for near-infinite ways to be applied, allowing it to be suitable to anyone, beginners can just sit down and play, while Veterans can constantly improve themselves and their tactics.

Color Tower DefenceFREE
All kinds of enemies entered the battlefield! Build your defenses against hordes of enemies!

Milky Way TD SURVIVORS AUTOBATTLER RTS$7.99
Milky Way is a unique mix of Tower Defense, RTS, Auto-Battler and Survivors. Build your base, choose random upgrades and use powerful skills to survive against hordes of enemies.

Milky Way TD SURVIVORS AUTOBATTLER RTS: EarthFREE
Milky Way is a unique mix of Tower Defense, RTS, Auto-Battler and Survivors. Build your base, choose random upgrades and use powerful skills to survive against hordes of enemies.

Mechanical Trap$5.99
Mechanical Trap is a 2D horizontal tower defense game with gravity effects, with a variety of defense towers to collect and use together, a rich map, each enemy has a different way of restraining, and each defense tower has a different function.It's challenging. Do you dare to accept the challenge?

Project Myriad 2$2.99
Project Myriad 2 is a tower defense strategy game. Build towers on a grid of hexagons floating in space. 35 levels with unique tiles and mechanics each providing a unique challenge. 3 difficulty levels including extreme mode which has never ending waves of enemies. Strive for your new high score!

Angels vs Demons$9.99
Welcome to the heavenly world, in which you have to fight with demons. They have surrounded the heavens and are trying to destroy everyone. But there are angels at your disposal, ready to expel the enemy.

Beware Planet Earth$4.99
Beware Planet Earth! is a beguiling mix of classic tower defense and time management coming to PC via Steam for the first time. Save your cows from the Martian invasion by building an effective defense using towers, traps and objects, and also by firing your Zapper directly at the invading force of little green men!

Defend from Candyland!$7.99
Step into the world of Defend from Candyland! where retro tower defense meets strategic depth. Plant and upgrade trees, use powerful buffs, and reveal enemy paths to shield Eden from waves of candy invaders. Master the challenge now!

Base Raid$4.99
Base Raid is a 2D base build and defence strategy game. In the game your goal is to build the best base to crush the enemy before it crushes you. You have a specific amount of in-game money to build your base and use it to fight against enemy bases.

Lesson Learned$9.99
Help Frank travel through history in this unique approach to the tower defense genre. Enter a bizarre daydream world in co-op or solo mode. Gather resources, build defense towers, and manage your minions. Take up the challenge and defeat the incoming enemies!

主动防御(Active Defense)$0.99
This is a strategy tower defense game where players need to choose the appropriate defense towers based on different maps and enemies. The game also offers a variety of defense towers, maps, and an endless mode waiting to be unlocked by the players!

Out of Order$5.99
New colours are constantly spawning - sort them faster than they arrive to win the round. Survive variations, purchase items, and even discover pets! Supports up to 4 local players.

Sleep Attack$6.99
Enjoy an amazing new TWIST in Tower Defense! You control the layout of the battlefield, and you decide the paths your enemies follow!

Mushroom Wars$9.99
Mushroom Wars is a dynamic real-time strategy game, where smart strategy meets furious action in epic PvP and PvE battles.

Cliff & Field Tower Defense$4.99
Use clever strategies and tricks to defend your new kingdom in this fast-paced, atmospheric and bullet-packed tower defense adventure.

Age of Goblins$4.99
AoG is a real-time strategy game (RTS) with simplified mechanics and cute visuals, but VERY challenging at times. Lead your goblin tribe into what they do best: expand, conquer, and exterminate each other. Any resemblance to humans is purely coincidental.

Broken Universe - Tower Defense$9.99
Get ready to rethink all your defense strategies! Build barricades to stop monsters, or lure them into a maze and attack. A variety of stages that change each time depending on how you play them.

MoonBeam$0.99
Here's a special forces team for you, they all have unique skills. Your task is to make the enemy die in a designated place. Get more energy.

Pathfinders: Memories$2.99
Memory is the key. Use it to help Pathfinders travel through time visiting ancient human civilizations and search for relics. The path to success is full of entrapments, obstacles, and enemies. Memorize them and draw the safe path for our heroes.

Car Wash TD - Tower Defense$9.99
A simple one-of-a-kind tower defense game where you need to wash cars before they reach the end of the road. Create mazes. Upgrade your towers. Wash all sorts of cars, trucks, boats, and planes.

Bees vs Zombees$7.99
In this Roguelike Tower defense, Zombees are approaching. Protect the hive by building powerfull turrets and utilizing the queen bee's abilities to fight off enemy hordes. Manage resources, strategize carefully, and wield spells to survive the ZUMBEECALIPSE.

I, Zombie$1.99
Quite a different zombie game - this time YOU are the zombie! Command your infested comrades, fight your way to freedom and let the zombie kind dominate the world! Oh, and you're able to create your own scenarios!

战地细胞(Battlefield Cell)$1.99
During the pandemic, would you be curious about how our bodies react to the virus? Are you wondering: "What' is autoimmunity?" "All definitions and thesis of the immunology are too hard to understand!" Don't be afraid! After beating the game, you get all the necessary information and fun!

OTTTD$7.99
Take command of HEROCORP™ and launch a Preemptive Defence Campaign™ against parallel dimensions in OTTTD, the most outrageous Tower Defence title around.

Bogdan's HeartQuest - The Invader Slayer$1.99
Princess Marcela is cursed! Bogdan is a knight trying to cure and protect his beloved girlfriend from reckless people that would do any thing to win the generous prize Marcela's desperate father offered for those who find a solution.

Four Mini Kingdoms WarFREE
Dig gold, chop trees, raise sheep, use these resources to recruit soldiers and build defenses.Wage war with the remaining three kingdoms, or play against friends in a LAN multiplayer game!

World of Turtle$4.99
Embark on a comical Sokoban-style puzzle adventure in World of Turtle! Solve 100 levels, collect delicious fruits, and reach the awaiting helicopter. Beware of cunning crocodiles and treacherous waters, as you navigate the levels. Can you outsmart the dangers and conquer this hilarious challenge?

Poly Bridge$9.99
Unleash your engineering creativity with an engaging and fresh bridge-building simulator with all the bells and whistles. Enjoy hours of physics-based puzzle solving in the Campaign and then jump in the Sandbox to create your own bridge designs and puzzles!

A Zombie Tail$10.8
Defeat waves of zombies in this strategy defense style game. Armed with a bone and several power ups, keep the zombies at bay as you battle across several levels, by timing and managing your attacks across 4 lanes. Will Roxy find her human before the zombies do!

Touhou Picross ~ Nazrin's Puzzles$3.99
Help Nazrin solve the incident of the mysterious puzzle craze spreading throughout Gensokyo!

Hush Hush High$5.99
SHHH! Hold onto those secrets! Step into the mind of a gossip monger as she navigates through the corridors of her high school and help her resist the urge to share every tantalizing piece of gossip with quick time events.

KannaSchool$9.99
『神奈学園』へようこそ!非常に面白くて革新的な横スクロールタワーディフェンスゲームです!

CreepWars TD$4.99
Summon units in to defend key positions. Defeat waves of creeps to earn gold to upgrade your defenders. Adjust your defense to the enemies’ armor type by choosing the right type of damage. Select different upgrade paths and be aware that some creeps have special abilities.

The Territory of Egg 2$4.99
The Territory of Egg 2 is an unique tower defense indie game. Place Egg Towers, choose evolution branches, combine skills and build defenses. The souls of Heroic Eggs await your awakening! Explore and gather resources in the dark forest, unlock the technology tree, and defeat even stronger enemies!

人类VS怪物(Human vs Monster)$5.99
"Human VS Monster" is a tower defense game similar to Plants vs. Zombies. You need to use humans reasonably to deal with monsters with different characteristics. There are at most five levels for each human or monster, which are-common, advanced, legend, antiquity, and creation.