Top similar games like Project: Vaccine A:
Project: Vaccine A FREE
Firewall, vaccine, cleaner... Place various blocks to protect your CPU! Vaccine A is a sandbox defense game, filled with parody of various programs.
Filters
Price (USD)
Release Date
Recommendations

Taur$24.99
Taur is an action-strategy sci-fi game. Control the Prime Cannon and unlock all of its powerful weapons and abilities. Build turrets, droids, aircraft and more as you fight to protect the homeworld of the Tauron droids against a relentless invasion. Will your Taur stand against the Imperion warmachine?

Creeping Dusk$6.99
Creeping Dusk is a tower defense game. Build a town around an abandoned gold mine and defend against monsters that swarm the area. Fortify your defenses, and prepare for the increasingly challenging nights. Will you be able to protect your town from the encroaching darkness?

Armoured Onslaught$17.99
Armoured Onslaught is a fast paced Top-Down Shooter and Tower Defence hybrid. You will need to make use of both strategy and skill as you fight your way through near endless hordes of deadly foes.

Protolife$11.99
Protolife is an unique tower-based strategy game which gives you a direct control over the builder robot in a struggle against the hungry proto-life organism.

Botanical TD$3.99
Defend against evil snails with a variety of plants in this Tower Defense while YOU have to make constant decisions how your enemies get stronger.

Guardians of the Sanctree$19.99
You and allies, avian inhabitants of Sanctree City, build structures and production lines on the tree, crafting weapons to fend off subterranean insects. Defense is just the start—dig deeper, destroy nests, fortify new defenses against escalating threats for an impregnable stronghold.

Dragon Spirits 0FREE
A skeleton from my childhood, the original edition of Dragon Spirits, which I developed in middle school, is a creature collector RPG that serves as the origin of the Dragon Spirits series. I still keep it as a memento. (Almost) no one can make a good game from the very beginning.

Terminal squad: Swarmites$3.99
Terminal squad: swarmites is a game with indirect control where you must erect a chain of buildings, which generate resources for construction or the combat units for destruction of an enemy.

League TD$3.99
"League Tower Defense" is a strategy tower defense game that combines unique defense towers and various upgradeable components to unleash different attack effects. Come and build your perfect defense line.

ZaciSa: Defense of the Crayon Dimension!$4.99
2D Tower Defense game set in a colorful world of Crayons. Over 20 different Maps with plenty of fun Weapons at your ready to defend the Crayon Empire. Can you survive the onslaught?

史莱姆冒险战SlimeWarfare$5.99
"Slime Warfare" is a rogue tower defense game with a variety of gameplay and placement.Slimes are weak monsters and always bullied by humans. Players will play the role of the Slime Queen to build structures to defend against adventurers' attacks and strengthen themselves.

Rescue HQ - The Tycoon$19.99
Build up your headquarters from scratch and design your own masterpiece. In Rescue HQ you build, organize and manage a joint station for firefighters, police and ambulance. Manage your resources wisely and master challenging emergencies to keep your city safe! Are you up to the challenge?

BARRICADEZ$18.99
Barricadez is a mix of tower defense and survival game. Take on your care robot and explore the underground, find new blueprints, gather resources and build your defenses and traps to survive through the night against a myriad of zombie-like creatures. Your goal: to defend the defenseless cradle.

Royal Wars: Farm TDFREE
Royal Wars: Farm TD is a free-to-play tower defense game where strategy meets luck. Place randomly selected towers, merge them to unlock higher tiers, and defend your kingdom through multiple levels. Plant crystals, manage resources, and prepare for epic battles.

Spark The Battle Dog$4.99
The boy Thomas contains the cure for zombie infection in his DNA, so he shouldn't be hurt. It's up to you to protect it from hordes of hectic zombies and other mutant animals. Upgrade your weapons, your camp and most importantly ...Survive! Are you prepared?

Infinitode 2 - Infinite Tower DefenseFREE
Infinitode 2 - a strategy in the Tower Defense genre, in which the player will have to build towers to protect his base from endless waves of enemies. The game features huge maps, lots of towers, resource miners, upgrade tree and map editor.

Bestion$1.99
Bestion is a game that combines Roguelike tower defense elements with automated factory construction. Players are required to construct their own factory on a planet and protect the kernel from monster attacks.

Castle Formers$10.0
Defend your castle from the attacks of the night creatures. Collect coins, interact with the elements of the game, discover, explore, learn and survive for 30 days or try again.

Towers & Goblins: The Last Stand$11.99
Build towers, manage resources, and lead units to defend your kingdom against goblins. Every decision you make determines your kingdom's fate.

Milky Way TD SURVIVORS AUTOBATTLER RTS: EarthFREE
Milky Way is a unique mix of Tower Defense, RTS, Auto-Battler and Survivors. Build your base, choose random upgrades and use powerful skills to survive against hordes of enemies.

ArcaneOutpost$4.99
A strategy game that combines MOBA and Tower Defence, You would control guardians with different skills,building your outpost to fend off enemy attacks.

Steel Covenant 钢铁盟约FREE
"Steel Covenant" is a 3D real-time strategy game. The game is set against the backdrop of World War II. Players can transform into Allied or German commanders, commanding multiple units to participate in battles

Survive In Strange World$4.99
Action adventure strategy game with tower defense, in a fantasy world, use your own combat skills, weapons, and the power of your partners to survive. Face the ultimate fate with your unique combat style.

ProtectHeartFREE
ProtectHeart is a strategic defense game, defend the heart at all costs! Are you up for the challenge?

Eye of the Void: Unleashed - Tower Defense$2.99
The goblin tribes of the realm have united against you and the power of the Eye of the Void. Build towers, fortify walls, construct gold mines to gather resources, and cast powerful spells to fend off waves of determined goblins and their allies who seek to destroy you.

Sheltered$14.99
Sheltered is a deep and emotional survival management game. You take on the role of protecting four family members who, after a global apocalypse, have found their way to a deserted shelter.

NecroCity: PrologueFREE
NecroCity: Prologue is just part of the gameplay that awaits you in the full version of the game. Take on the role of the young Prince of Undead, trying to prove himself in the world of the Undead Kingdom. Push back the hordes of monsters and build your fortress! 🔥

Pest Control in the Crypt$2.99
Pest Control in the Crypt is a strategic rogue-like wave-battler. Enhance your elemental potions with unique items and a branching skill tree to slay Pests. Delve into the Abyss and conquer the Crypt.

CyberGrid: Tower defenseFREE
Tower defense is a Tower defense game containing HQ, Tower, and 3 building that generates resources. In order to build a building, you must have enough resources. Each building can generate different resources. You must protect the HQ from the Enemy

Tomb Of AnuBI0S$9.99
Tomb of AnuBI0S is an unique 2D tower defense-platformer with an Egyptian Sci-fi setting. Defend the AI deity RAm from waves of undead "Organics." Upgrade your arsenal from weapons to walls, turrets, and your player capabilities. Immerse yourself in meticulously crafted levels and defend RAm!

Orrstead$12.99
Orrstead is a relaxing city builder that combines resource management and incremental game mechanics. Unlock technologies, complete quests, and adapt to the changing seasons.

Crush Link TDFREE
A Tower Defense game with new mechanics in virtual setting about online dating. Your task is to protect your base preventing spam from getting into your inbox. Build towers in marked places to stop spam.

Mechanic Miner$7.99
Put your mechanical skills to the test in a physics-based sandbox where ingenuity and creativity are the ultimate key to survival. Construct fantastical machines, gather resources, acquire new technologies to battle dangerous enemies and use your imagination to shape your world.

Idle Monster TDFREE
An endless Tower Defense game of epic Monsters vs evil War Machines. Unlock and upgrade tons of unique elemental Monsters (Water, Air, Earth, and Fire) to defend your home from an infinite swarm of robots. Strategize the most effective placement of Monsters to synergize their elemental abilities.

Kill A Million Rats$10.99
A base-building, Roguelike Action/Turn-based Strategy (RATS) game, in a forest invaded by a million Rats. As the powerful Spirit of Vengeance, you must save the adorable Villagers! Explore a randomly generated world, expand your village, and exterminate the Rats!

Kingdom: ClassicFREE
Kingdom is a 2D sidescrolling strategy/resource management hybrid with a minimalist feel wrapped in a beautiful, modern pixel art aesthetic.

The Last Roman Village$2.99
The Last Roman Village is a strategy defence game that gives freedom to develop a whole Roman city from scratch and to wisely choose the way to defend it. The game allows players to experience variety of options and creativity.

SpiderPunks$9.99
SpiderPunks is a unique blend of three-game genres: Builder/Defense, Action, and Puzzle. Earn money and spend it on new spider's web connections. Buy new spiders or heal injured ones. Get experience to develop more spider's skills to fight against toxic soap bubbles.

GardaFREE
Garda is a 2d pixel art tower defense and exploration game. Protect your totem that is keeping your world out of the darkness. Wander across an immense desert. Learn about the weird laws of this world by using technology and energy systems to power defense turret against the numerous enemies…

Defend from Candyland!$7.99
Step into the world of Defend from Candyland! where retro tower defense meets strategic depth. Plant and upgrade trees, use powerful buffs, and reveal enemy paths to shield Eden from waves of candy invaders. Master the challenge now!

Save and Conquer : 8 YearsFREE
This is a 2D defense game that depicts the near future that may arise from climate change. Unlike the defense game, which is automatically attacked by traditional turrets, it is an attractive game that requires you to defeat the enemy by operating the turret directly with limited power.

Tower defense for virus$1.99
Defend your computer from incoming viruses using powerful turrets!Tower Defense for Virus is a tower defense game with rogue-lite elements. Strategically place your turrets to quickly eliminate waves of viruses and protect your system from the ever-growing threat.

GemCraft - Frostborn Wrath$12.99
The epic tower defense dark fantasy journey continues! Create powerful gems with various abilities and take on the battle against an endlessly flowing army of monsters, and face the growing darkness as you fight your way back towards the Spiritforge.

Defensurvivor$10.99
DEFENSURVIVOR is a strategy game where you build obstacles and place and move units to block zombies. There are various units with unique characteristics and powerful high-level units that can be obtained through combination. Use randomly given units to survive until the end!

Block of Rum$1.99
Block of Rum is a sandbox dedicated to building sailing ships and piracy.

Forts$14.99
Unleash your creativity and strategic prowess in Forts, the exhilarating physics-based RTS! Design, construct, and customize imposing fortresses, bristling with devastating firepower, and blast your opponent’s buildings to rubble!

泉水镇·居民的反击💩$5.99
This is a lightweight overhead shooting game, 1 can operate with one hand, collect gold coins by killing monsters in the game, and then organize an expedition to find the missing members.

Neural Shock$5.99
In Neural Shock, you must cleanse the world of horrid and bloodthirsty creatures by utilizing turrets, traps, wits and weapons. Choose from different class choices with unique playstyles and over 20+ different turrets and traps in this unique sci-fi Tower Defense / Action RPG.

Eclipse Horde$8.99
"Craft or die" It's up to you to decide. The solar eclipse will come 30 days later. Can you survive the raid of the day? The sandbox and survival crafting game where you can do everything you want.

Box Nation [] Lets Go Build and Fight$199.99
Box Nation [ ] is a sandbox kind of game. In this box world, you can become a leader of your own nation. Your main goal in the game is to create and develop your nation of boxes.

8BitMMOFREE
8BitMMO is a retro-style 2D massively multiplayer game! It's a giant construction sandbox -- you can build a home or a castle in a persistent streaming world. Found and manage your own city. Fight evil LawyerCats and engage in Player vs Player battle.