Top similar games like Project: Vaccine A:
Project: Vaccine A FREE
Firewall, vaccine, cleaner... Place various blocks to protect your CPU! Vaccine A is a sandbox defense game, filled with parody of various programs.
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Armoured Onslaught$17.99
Armoured Onslaught is a fast paced Top-Down Shooter and Tower Defence hybrid. You will need to make use of both strategy and skill as you fight your way through near endless hordes of deadly foes.

Rescue HQ - The Tycoon$19.99
Build up your headquarters from scratch and design your own masterpiece. In Rescue HQ you build, organize and manage a joint station for firefighters, police and ambulance. Manage your resources wisely and master challenging emergencies to keep your city safe! Are you up to the challenge?

Creeping Dusk$6.99
Creeping Dusk is a tower defense game. Build a town around an abandoned gold mine and defend against monsters that swarm the area. Fortify your defenses, and prepare for the increasingly challenging nights. Will you be able to protect your town from the encroaching darkness?

Taur$24.99
Taur is an action-strategy sci-fi game. Control the Prime Cannon and unlock all of its powerful weapons and abilities. Build turrets, droids, aircraft and more as you fight to protect the homeworld of the Tauron droids against a relentless invasion. Will your Taur stand against the Imperion warmachine?

Spark The Battle Dog$4.99
The boy Thomas contains the cure for zombie infection in his DNA, so he shouldn't be hurt. It's up to you to protect it from hordes of hectic zombies and other mutant animals. Upgrade your weapons, your camp and most importantly ...Survive! Are you prepared?

Guardians of the Sanctree$19.99
You and allies, avian inhabitants of Sanctree City, build structures and production lines on the tree, crafting weapons to fend off subterranean insects. Defense is just the start—dig deeper, destroy nests, fortify new defenses against escalating threats for an impregnable stronghold.

League TD$3.99
"League Tower Defense" is a strategy tower defense game that combines unique defense towers and various upgradeable components to unleash different attack effects. Come and build your perfect defense line.

Dragon Spirits 0FREE
A skeleton from my childhood, the original edition of Dragon Spirits, which I developed in middle school, is a creature collector RPG that serves as the origin of the Dragon Spirits series. I still keep it as a memento. (Almost) no one can make a good game from the very beginning.

Royal Wars: Farm TDFREE
Royal Wars: Farm TD is a free-to-play tower defense game where strategy meets luck. Place randomly selected towers, merge them to unlock higher tiers, and defend your kingdom through multiple levels. Plant crystals, manage resources, and prepare for epic battles.

Botanical TD$3.99
Defend against evil snails with a variety of plants in this Tower Defense while YOU have to make constant decisions how your enemies get stronger.

8BitMMOFREE
8BitMMO is a retro-style 2D massively multiplayer game! It's a giant construction sandbox -- you can build a home or a castle in a persistent streaming world. Found and manage your own city. Fight evil LawyerCats and engage in Player vs Player battle.

Idle Monster TDFREE
An endless Tower Defense game of epic Monsters vs evil War Machines. Unlock and upgrade tons of unique elemental Monsters (Water, Air, Earth, and Fire) to defend your home from an infinite swarm of robots. Strategize the most effective placement of Monsters to synergize their elemental abilities.

史莱姆冒险战SlimeWarfare$5.99
"Slime Warfare" is a rogue tower defense game with a variety of gameplay and placement.Slimes are weak monsters and always bullied by humans. Players will play the role of the Slime Queen to build structures to defend against adventurers' attacks and strengthen themselves.

Castle Formers$10.0
Defend your castle from the attacks of the night creatures. Collect coins, interact with the elements of the game, discover, explore, learn and survive for 30 days or try again.

ZaciSa: Defense of the Crayon Dimension!$4.99
2D Tower Defense game set in a colorful world of Crayons. Over 20 different Maps with plenty of fun Weapons at your ready to defend the Crayon Empire. Can you survive the onslaught?

ProtectHeartFREE
ProtectHeart is a strategic defense game, defend the heart at all costs! Are you up for the challenge?

Defensurvivor$10.99
DEFENSURVIVOR is a strategy game where you build obstacles and place and move units to block zombies. There are various units with unique characteristics and powerful high-level units that can be obtained through combination. Use randomly given units to survive until the end!

Survive In Strange World$4.99
Action adventure strategy game with tower defense, in a fantasy world, use your own combat skills, weapons, and the power of your partners to survive. Face the ultimate fate with your unique combat style.

Towers & Goblins: The Last Stand$11.99
Build towers, manage resources, and lead units to defend your kingdom against goblins. Every decision you make determines your kingdom's fate.

Sheltered$14.99
Sheltered is a deep and emotional survival management game. You take on the role of protecting four family members who, after a global apocalypse, have found their way to a deserted shelter.

Bestion$1.99
Bestion is a game that combines Roguelike tower defense elements with automated factory construction. Players are required to construct their own factory on a planet and protect the kernel from monster attacks.

NecroCity: PrologueFREE
NecroCity: Prologue is just part of the gameplay that awaits you in the full version of the game. Take on the role of the young Prince of Undead, trying to prove himself in the world of the Undead Kingdom. Push back the hordes of monsters and build your fortress! 🔥

Eye of the Void: Unleashed - Tower Defense$2.99
The goblin tribes of the realm have united against you and the power of the Eye of the Void. Build towers, fortify walls, construct gold mines to gather resources, and cast powerful spells to fend off waves of determined goblins and their allies who seek to destroy you.

Crush Link TDFREE
A Tower Defense game with new mechanics in virtual setting about online dating. Your task is to protect your base preventing spam from getting into your inbox. Build towers in marked places to stop spam.

Dungeon Origins$9.99
Betrayed by the kingdom, the hero seeks his revenge as a new dungeon master! Build and manage your dungeon, raid villages, unlock new evolutions, grow an army of powerful monsters and then fulfill your revenge against the kingdom!

Phoenix Hope$11.99
Phoenix Hope is a pixel art 2D real-time, side-view strategy game in which you must develop your colony during the day and repel waves of monsters at night.

CyberGrid: Tower defenseFREE
Tower defense is a Tower defense game containing HQ, Tower, and 3 building that generates resources. In order to build a building, you must have enough resources. Each building can generate different resources. You must protect the HQ from the Enemy

SpiderPunks$9.99
SpiderPunks is a unique blend of three-game genres: Builder/Defense, Action, and Puzzle. Earn money and spend it on new spider's web connections. Buy new spiders or heal injured ones. Get experience to develop more spider's skills to fight against toxic soap bubbles.

Junkyard WarFREE
Junkyard War is a unique take on the tower defense genre. Clear trash from the junkyard and recycle it into valuable resources while holding off waves of your competitor's army trying to make the trash disappear by burning it all down!

Save and Conquer : 8 YearsFREE
This is a 2D defense game that depicts the near future that may arise from climate change. Unlike the defense game, which is automatically attacked by traditional turrets, it is an attractive game that requires you to defeat the enemy by operating the turret directly with limited power.

Kill A Million Rats$10.99
A base-building, Roguelike Action/Turn-based Strategy (RATS) game, in a forest invaded by a million Rats. As the powerful Spirit of Vengeance, you must save the adorable Villagers! Explore a randomly generated world, expand your village, and exterminate the Rats!

Kingdom: ClassicFREE
Kingdom is a 2D sidescrolling strategy/resource management hybrid with a minimalist feel wrapped in a beautiful, modern pixel art aesthetic.

Witch and Hero(魔女と勇者)$4.99
Witch & Hero is an 8-bit style action game. You play as a hero accompanied by a witch taking on the evil Medusa, whom has destroyed many villages and towns with the monsters that stand before her.

Infinitode 2 - Infinite Tower DefenseFREE
Infinitode 2 - a strategy in the Tower Defense genre, in which the player will have to build towers to protect his base from endless waves of enemies. The game features huge maps, lots of towers, resource miners, upgrade tree and map editor.

The Last Roman Village$2.99
The Last Roman Village is a strategy defence game that gives freedom to develop a whole Roman city from scratch and to wisely choose the way to defend it. The game allows players to experience variety of options and creativity.

BARRICADEZ$18.99
Barricadez is a mix of tower defense and survival game. Take on your care robot and explore the underground, find new blueprints, gather resources and build your defenses and traps to survive through the night against a myriad of zombie-like creatures. Your goal: to defend the defenseless cradle.

Lords and Villeins$24.99
Build a prosperous settlement in a unique simulation of a feudal economy - each family runs their shop, owns their goods, and trades with other villagers in a free market. You will manage the land, build houses, organise events, set taxes, and balance supply and demand while engaging in diplomacy!

GardaFREE
Garda is a 2d pixel art tower defense and exploration game. Protect your totem that is keeping your world out of the darkness. Wander across an immense desert. Learn about the weird laws of this world by using technology and energy systems to power defense turret against the numerous enemies…

Night Light$3.99
Defend against the creatures of that night! Protect yourself and your lamp by building and upgrading your base. Equip yourself with the best weapons to deal with the incoming waves.

Tomb Of AnuBI0S$9.99
Tomb of AnuBI0S is an unique 2D tower defense-platformer with an Egyptian Sci-fi setting. Defend the AI deity RAm from waves of undead "Organics." Upgrade your arsenal from weapons to walls, turrets, and your player capabilities. Immerse yourself in meticulously crafted levels and defend RAm!

Ice Fighter$2.99
Ice Fighter is a fast-paced Tower Defense-like game where you battle enemies, scavenge for resources, manage upgrades, and build defenses. Melt enemies during the night and gather resources during the day.

Milky Way TD SURVIVORS AUTOBATTLER RTS: EarthFREE
Milky Way is a unique mix of Tower Defense, RTS, Auto-Battler and Survivors. Build your base, choose random upgrades and use powerful skills to survive against hordes of enemies.

泉水镇·居民的反击💩$5.99
This is a lightweight overhead shooting game, 1 can operate with one hand, collect gold coins by killing monsters in the game, and then organize an expedition to find the missing members.

Tower defense for virus$1.99
Defend your computer from incoming viruses using powerful turrets!Tower Defense for Virus is a tower defense game with rogue-lite elements. Strategically place your turrets to quickly eliminate waves of viruses and protect your system from the ever-growing threat.

SolitariusFREE
Solitarius is a 2D top-down wave shooter set in a sci-fi space environment. It is a free minigame that contains six different levels, eight different enemies and nine different weapons. Instead of surviving as long as possible you have to make it through each level.

Jin Conception$14.99
Jin Conception is a social deduction fantasy thriller turn based souls-like JRPG. Go on an adventure not knowing which party member is friend or foe. Solve clues to progress the story.

Xander the Monster Morpher: Universe Breaker$4.99
A Monster-Catching top-down shooter! Fuse monsters together to create the ultimate team!

Planetary Defense: An Orbital Turret Defense System$1.99
2D space shooter and turret defense come together to create the Planetary Defense System this world needs! Shoot down asteroids and aliens and survive the bosses in this arcade like game featuring customizable satellites, projectiles, and upgradable Cannon and Planet Shield systems.

Nova Lands$19.99
Nova Lands is a factory building, exploration, and island management game. Explore, engage in combat, and automate your industry. The planet you’re on is full of mysteries, creatures, people, and things to do. Welcome to your new home amongst the stars!

Pest Control in the Crypt$2.99
Pest Control in the Crypt is a strategic rogue-like wave-battler. Enhance your elemental potions with unique items and a branching skill tree to slay Pests. Delve into the Abyss and conquer the Crypt.

---Red---Tether-->$12.99
---Red---Tether--> is an action-packed “combat-puzzle” roguelite. You will tear apart massive space fleets, using nothing but your advanced tether harpoons. Pull and crash ships into another, rip their components off, then grapple-swing your way out of danger.