Top similar games like Anomaly Defenders:
Anomaly Defenders $9.99
Anomaly Defenders is the closing installment of the Anomaly series. The original incarnation of the Tower Offense sub-genre had players controlling humans fighting alien invaders. Now, the tables have turned. The human counterattack is underway and the alien homeworld is under threat.
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Volcan Defend the Tower$14.99
A solo development and the first game of Processor Game Studios presents "VOLCAN defend the Tower". A third person shooter on an open world sci-fi game, play as Sollum to defend your Volcan Towers against your enemies while exploring a planet earth with nature restored

X-Morph: Defense$19.99
Unique fusion of a top-down shooter and tower defense strategy. You are the invader! Use destructive weapons or lead your enemies into a maze of towers. Strategize in the build mode by carefully selecting various types of alien towers or throw yourself right into the heat of the battle.

Pipeline Panic$3.99
Good old fashioned 2D arcade fun with tons of upgrades and fast paced action where taking risks is rewarded with a higher score. Defend humanity's last source of energy wrench in one hand, laser gun in the other

Tower Defense - Fantasy Legends Tower Game$4.99
Tower Defense - Fantasy Legends TD Game - Defend your Magic Kingdom against legendary villains like hordes of trolls, orcs, wizards, witches and undead monsters!In this Castle defense game you will have to think strategically to build towers!Fight the hordes in this strategy defense game!

Zombie DefenseFREE
A modern hybrid of the classic RTS and modern Tower Defense. Recruit soldiers, place them on slots and let them shoot incoming waves of zombies by their own. Order supplies, throw grenades, order airstrikes and many more... Perfect mix of strategy, tactics and micromanagement.

Alien Robot Monsters$5.99
Epic sci-fi tower defense action with 16-bit era look and feel, pitching your colonists against an almost endless horde of hostile alien robots who strongly oppose your attempts of colonizing their planet! Deluxe version includes the soundtrack!

AIRA VR$9.99
You believed tower defense is only about building towers? That's not quite right – because AIRA VR is not like other tower defense games in virtual reality. Once the battle starts you find yourself in the midst of the fight!

Damn Endless Orcs$1.99
Damn Endless Orcs is set in a medieval fantasy world, where human heroes battle relentlesly against an (you guessed it) endless horde of orcs. In this game you must survive and gather equipament to fight the horde and become earths mightiest hero.

Outflow$2.99
Experience Atlas’s journey in the future world to save his planet. Beat the enemies with unique mechanics and explore a huge open world in this action RPG.

Forge Squad$17.99
Forge Squad is a cooperative crafting game for up to 4 players. Forge runes to defeat the approaching waves of enemies. Help your friends to complete multi-step recipes faster. Charge towers with the right type of runes to obliterate your enemies.

Astral Guardian$9.99
Build various towers to resist the large number of monsters coming from the wormhole, by extending their walking routes.

Cubemen 2$7.99
Cubemen 2 is a fast paced, action packed, original 3D Strategy game where you use your little Cubemen units to defend and attack enemies in a range of awesome game modes including CTF, Skirmish, Territory and more.

星旅:前奏 Wandering Planet: Prelude$3.99
Star Trek: Prelude is a space-based game that builds defense towers on earth to defend against alien invaders called Black Ember.

Assault On Metaltron$6.99
Get ready to defend your metallic planet from human and orc invaders in this intense, challenging and addictive action tower defense game! Play solo or in cooperation on one pc!

Cliff & Field Tower Defense$4.99
Use clever strategies and tricks to defend your new kingdom in this fast-paced, atmospheric and bullet-packed tower defense adventure.

Project Astra Dominium$9.99
Project Astra Dominium is a Tower Defense game with Basebuilding and Automation elements. Build up your base to become a supply hub for Earth's desperately needed materials, gather resources while defending against an unknown alien threat and improve your tower's and AI capabilities.

Defense Grid: The Awakening$9.99
Defense Grid: The Awakening is a unique spin on tower defense gameplay that will appeal to players of all skill levels. A horde of enemies is invading, and it's up to the player to stop them by strategically building fortification towers around their base.

Touhou Monster TD ~ 幻想乡妖怪塔防$18.99
Easy to learn but hard to master, Touhou Monster TD is a unique Tower defense Game. Control your character, level up and unlock tower skills and character talents, use your wisdom to defeat incoming enemies. Travel the Gensokyo, find out why the “Incident” happened this time.

Prime World: Defenders$9.99
Fight off hordes of monstrous mutants created from a strange cataclysmic event in the new tower defense game, Prime World: Defenders. Join a group of exile treasure hunters who have ventured into the capital of an ancient empire, vast with mystery and danger.

Freaking Meatbags$9.99
Land on a planet, pick up some rocks, leave before the solar system explodes. Oh, and don't die in the nightly robot attacks! Freaking Meatbags is a humorous real-time strategy game that's all about building a base, mixing meatbag DNA, then convincing those dolts to help you gather resources.

Secrets of Magonia$7.99
In this tower defence game, you enter the world of Magonia and defend it against hordes of humans, orcs, ogres and other evil forces. Fight in different areas and adapt your strategy to the terrain and the enemy forces.

Tower Defense: Last Castle$3.99
In the depths of an ancient forest, your castle the last human stronghold stands as the final bastion against a monstrous horde. Strategize your defense by employing soldiers, traps, towers, and even the monsters themselves.

Defense of the Sodomites$0.99
An exciting tower defense game where you have to defend your people from the invasion of enemy forces. Your task is to build and upgrade cannons to fend off waves of attacking enemies.

Alien Invasion Tower Defense$1.99
Alien Invasion TD is a new strategy 3D game with an exciting new design, campaign mode, endless mode, players custom-built levels and PVP online multiplayer, defend against waves of approaching enemies by placing your defense towers, recruiting units,use special attacks, boosts and more.

Inbound UFO$7.99
With a style inspired by the RTS games from early 2000's, a new tower defense combines in a unique way action, tactics, replay value and fun. They are here! Choose your targets, upgrade, replay, discover your enemies and your tactical skills.

Samawa Idle$4.99
Unleash the power of specialized towers to annihilate hordes of monsters in this idle game with roguelike elements. Collect gold, level up your towers, face powerful bosses, and refine your strategy with an evolving skill tree.

Oil and SandFREE
An exciting tower defense game where you have to defend your island from the invasion of enemy forces. Your task is to build and upgrade towers to repel waves of attacking enemies.

Anomaly 2$14.99
Anomaly 2 is a sequel to the critically acclaimed Anomaly Warzone Earth. Maintaining the core elements of the original, Anomaly 2 adds plenty of new features: unit morphing, over million tactical combinations, post-apo world and tower defense vs tower offense multiplayer mode.

SaranityFREE
Saranity a 3rd person game, mixing elements from multiple genres into 1 game. Featuring Single player, COOP and Versus game modes playing with or against your friends. Action and Gameplay is what counts. Can you holdout longer than your friends while sending boss units and go in PVP style.

Stardrift Nomads$9.99
Stardrift Nomads is a dual-stick shooter with a focus on cooperative play and retro action. Build and upgrade 12 unique towers, customize your ship to fit your play style, and seize victory with up to 8 players!

HexDefense$5.0
HexDefense is a roguelike tower defense with an emphasis on constant action with little to no downtime. Defend your city by building towers, upgrading them with money from your fallen foes, and equipping them with strange items you find out in the world!

Faith & Shield:4044 Tower Defense$4.99
Faith & Shield: 4044 Tower Defense game, where you protect the human settlement from the incoming invaders, robots and other creatures, never seen before on our planet.

Super Sanctum TD$4.99
Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core!

M.A.C.E. Tower Defense$2.99
M.A.C.E. Tower Defense is a classic tower defense game with unique towers and enemies and an ingame shop system for getting better towers, upgrade existing towers and buy special items.

Capers vs Pirates$0.99
Capers vs Pirates is an exciting 3D tower defense game where players take on the role of cunning capers defending their treasures from raids by greedy pirates. In this game, you will need to set up the perfect defense as the game is challenging. Use your strategic thinking!

QANGA$19.99
QANGA: Dive into a sci-fi adventure of exploration and resilience across the cosmos. Merge your mind with a state-of-the-art cyborg crafted by ICLab's Industry labs, and journey through this expansive universe!

Mythic Defender$4.99
In this VR game combining Tower Defense & Archery, dexterity and strategy will be your best allies to help the gods to protect their kingdom against mythological creatures! Grab your bow and join this epic fight. Will you be able to defeat all enemies and keep the treasure of the gods safe?!

Towers of Altrac - Epic Defense Battles$0.99
Towers of Altrac is a 3D Tower Defense cooperation game for up to 4 players with an innovative A.I. system “S.A.D.”, which makes your enemies intelligent . Fight against the horde of Goblins, Orcs, Dragons and other monsters on 62 unique maps. The game is for every level of player experience.

Project MyriadFREE
Project Myriad is a tower defense strategy game. You build towers on a map of hexagons that will attack and defeat oncoming waves of enemies. Towers can be upgrade and some have varied upgrade paths. The goal is clear as many waves as possible. How far can you get?

Medieval Defenders$4.99
Defend your ancestral castle – show the invader who the master is! Build towers, save money, train your spells, and your enemy will be vanquished.

Trial Of Empires TDFREE
Trial of Empires TD, is a Free to Play 3D tower defense game. Pick your ally and build your strategy with different combinations. Compete with other players on the Leaderboards with Single-Player or CO-OP game modes

Robowars$3.99
Robowars is back on Steam! Fight off troops of droids for freedom and honor in our classical tower defense game. Lead the forces of the Solar Union to protect the peaceful planet of Praymos from the aggressive Trade Confederation.

Hold The Fort$4.99
Dive into intense, fantasy, tower defense action! Using turrets, spells, and your cunning, you must defend your kingdom against an onslaught of enemies launching a surprise attack while the king is away.

Discharge$9.99
Lead your drones into an epic battle for the last iridium on the planet.

Extinction Eclipse$9.99
You are in command of the human fleet, searching for asteroids to mine, extract resources and build bases and more ships to defeat aliens invaders. This simple and short action RTS has a full and exciting campaign, and a skirmish mode that allows you to play a different mission on every match.

Sanctum 2$14.99
Sanctum 2 is the sequel to the world’s first Tower Defense/FPS hybrid game. Pick from four unique character classes and embark on a mission to protect the oxygen-producing Cores from hordes of deadly aliens who are threatened by their existence.

Steampunk Syndicate$1.99
Steampunk Syndicate is a tower defense with elements of collectible card games.

Infectonator 3: Apocalypse$12.99
A campy, crazy pixelart zombie apocalypse arcade sim where you're the bad guy. Drop your virus and spread it across the globe while you unlock a whole horde of bizarre undead to do your bidding.

Magic Quest$1.99
Magic Quest is a tower defense game with towers, mighty enemies, bosses and heroes with unique abilities.

Guardians: Royal JourneyFREE
1000+ levels tower defense

All Noobs must die$2.99
A place where wishes come true! You just need to protect the obsidian portal from zombies. Mine resources with your pickaxe, build traps, and put them to use — let them grind the zombies into a juicy green porridge! Funny meme endings!