Top similar games like Intelligent Design: An Evolutionary Sandbox:
Intelligent Design: An Evolutionary Sandbox $6.99
A toy ecosystem with fully simulated genetics and evolution. Will you tinker with DNA or sit back, relax, and see if life finds a way?
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SynthetiCell BioClicker$5.99
SynthetiCell BioClicker is an Idle incremental simulator where you bring to life a colony of synthetic automaton cells. Inspired by the classic 'Game of Life' by mathematician John Horton Conway (1970) about the evolution of an organism. Can you guide your colony to prosperity?

Ecosystem$19.99
Create virtual lifeforms whose development is shaped by a deep simulation of evolution. Guide them as they fight, mate, and adapt to the environment you have built. All the creatures in the trailer evolved on their own in the game!

Beetle Uprising$9.99
Collect, raise and breed an army of beetles to rise up and lay claim to the abandoned lot! The game features a complex genetics simulation and real-time tactics missions with a full campaign.

Territory: Animals Genetic Strategy$6.99
Strategy game about genes and animal species. Evolve, reproduce, expand to new territories, survive, and fight to achieve various goals like biodiversity or dominance in the ecosystem.

Natural Instincts: European Forest$9.99
Protect the environment, and save it from harm! Give commands to the animals, observe their rituals and help them survive. Face different disasters, react to human presence and help the animal kingdom flourish in this unique, environmental experience!

Creatura$14.99
Seed, Breed, Create. From single cell organisms to complex ecosystems. Evolve every part of your own unique aquarium / terrarium by applying scientifically accurate principles of natural and artificial selection, in Creatura - ultimate Virtual Evolution Vivarium Simulator.

Deisim$14.99
Live the experience of being a powerful god and create the world to see the growth of mankind.

Reus 2$24.99
Shape worlds with your godly titans. Make symbiotic ecosystems and inspire humanity with your creations. Their achievements unlock new possibilities. Make different planets for different human spirits, and fill the universe with life!

Gridworld$0.99
Gridworld is an artificial life / evolution simulator in which abstract virtual creatures compete for food and struggle for survival. Conditions in this two-dimensional ecosystem are right for evolution to occur through natural selection.

Sap: School DaysFREE
Be the unseen hand, guiding surreal life across a grid of possibility. Plant the seeds of biomes, creatures, and whimsical machines. Watch your strategic decisions etch vibrant stories. How long can your world survive?

Small Living World$4.99
An ecosystem simulation running in your hands. Transform a desertic world into a lush forest. No stress, play at your own pace. This world is at your disposal. Terraform the landscape, add plants and animals. Create your perfect ecosystem.

Prehistoric Kingdom$29.99
Take control of limitless power in Prehistoric Kingdom to build, manage and grow the ultimate zoo for extinct animals.

Equilinox$9.99
Equilinox is a relaxing nature simulation game in which you can create and nurture your own ecosystems. Shape the world to your liking, cultivate and raise hundreds of different species, and evolve your wildlife to unlock more exotic plants and animals.

Pets Hotel: PrologueFREE
Pets Hotel: Prologue is just part of the gameplay that awaits you in the full version of the game. Pets Hotel: Prologue gives you a unique opportunity to build, design, and run a place where pets can feel at home. Cats, dogs, turtles, and many other animals are waiting for you to take care of them!

Universe Sandbox$29.99
Create & destroy on an unimaginable scale with a realistic physics-based space simulator. Explore the beauty of our universe and the fragility of our planet. Use science to bend the laws of gravity, collide planets, boil away oceans, fire epic space lasers, and customize your universe.

Synergy$24.99
An ecosystem City Builder in a unique world. Build your settlement, manage your workers and optimize your resources. Analyzing your environment, spreading new plants, and harvesting them are key to prosperity.

Autonauts$19.99
In Autonauts you must build, create, and automate. Start by establishing a colony, crafting bots and teaching them via Scratch-style programming to build an ever evolving autonomous paradise of agriculture, industry and enlightenment.

EcoGenesis$2.99
EcoGenesis is a 2D black-box ecosystem simulator where you need to craft an ecosystem that can withstand the test of time. You must unlock creatures and balance your environment while driving towards one of the three victory conditions in this turn-based simulation.

Aquarium Designer$9.99
Aquarium Designer gives you an opportunity to create the aquarium of your dreams! Become a professional whose job is to design it, build it, and fill it with the various underwater wildlife! All types, all sizes - your creativity is your only limit!

Maia$24.99
Maia is a colony building game set in the not-so-distant future. Your colonists make planetfall on a hostile world and you must ensure their survival and their safety, constructing their off-world habitat from almost nothing and sheltering them from a dangerous, often deadly environment.

Space Haven$22.99
Embark on a space voyage with your ragtag crew of civilians in search of a new home. Build spaceships tile by tile, create optimal gas conditions, manage the needs and moods of their crew, encounter other space-faring groups, and explore the universe in this spaceship colony simulation.

Farming Life$9.99
Are you tired of corporate life? Create your own farm! Plant vegetables and fruits, harvest crops, employ workers, take care of animals. Buy farm equipment, manage employees and just relax!

Founders' Fortune$21.99
A fantasy village builder focusing on creative building, colonist psychology and base defense. Handle resources, farming, production, tools, diplomacy, families, trading, defense, and research, as well as the wishes, expectations, thoughts, and equipment of every villager.

Stardeus$29.99
Stardeus is a deep colony sim set on a broken starship manned by drones and hibernating human survivors. As the AI, have your drones repair your ship, save your crew and travel the stars in this beautiful simulation.

Candy Machine$7.99
Run a candy factory. Place machines and conveyors and feed them different mixtures of ingredients to create candy

ZooKeeper$9.99
Become a Zoo Keeper, manage and build the zoo of your childhood dreams! Take care of the animals and create ideal conditions for them. Grow your zoo, add extraordinary species and prepare amazing attractions for visitors.

Hell Architect$24.99
Hell Architect is a game about building and managing your own hell. You take on a role of a hell manager and are tasked with developing the underworld in a way that would make Lucifer himself fall off his chair.

Before We Leave$19.99
Before We Leave is a city building game set in a cozy corner of the universe. Nurture your Peeps and their surroundings while rebuilding and rediscovering civilisation. Settle new lands and planets while avoiding hungry Space Whales.

A Game of Humans$11.99
A sandbox village simulation fundamentally about people, their thoughts and their needs. Luckily they are not alone in their burden, for you possess divine powers. And you would surely never add to the plight of the common man... Right?

Laysara: Summit Kingdom$19.99
Build and expand your very own settlements in high mountains! Carefully plan production chains and satisfy various needs of your three-caste society while dealing with mountain hazards such as weather breakdowns and avalanches. Are you skilled enough to make your town thrive?

Island Master$4.99
Build, manage, and thrive in Island Master! Procedural islands, resource control, citizen happiness. Become the ultimate Island Master in this top-down city builder.

Project AURA$14.99
Project Aura is a micro management game where you lead a Colony of Climate Disaster Survivors. You have been assigned the mission to build an habitat capable of survival in this new unknown world.

Oxygen Not Included$24.99
Oxygen Not Included is a space-colony simulation game. Deep inside an alien space rock your industrious crew will need to master science, overcome strange new lifeforms, and harness incredible space tech to survive, and possibly, thrive.

Foundation$34.99
Foundation is a grid-less, laidback medieval city-building game with a focus on organic development, monument construction and resource management.

Snowtopia: Ski Resort Builder$24.99
Build your ideal ski resort. Keep skiers smiling with fresh pistes and fine facilities. Ski, build and chill in the wintry world of Snowtopia where everyone is welcome!

Power of the Ancients$5.99
A mostly peaceful pixely isometric city builder with a bit of magic. Four different people live in the four quadrants of the pyramid. Fishermen, farmers, fire people, magicians. Gather resources, build homes, challenge demons and create a thriving city while preparing for winter.

Space Architect$9.99
Design your dream space station in Space Architect! Master the power of automation or 'hire' an army of crewmates to handle your ever-growing production. Mine asteroids, fabricate goods, and engage in interstellar trade to pay off the menacing Big Evil Corp. Will you thrive in the vastness of space?

New Home: Medieval Village$19.99
New Home Medieval Village is a zoning-based medieval themed city building game. Create zoning areas according to the demands of the villagers and meet the needs of the villagers. Keep them happy with your service buildings and attract wealthier villagers to your village.

Blockchain Tycoon$14.99
Blockchain Tycoon is the cryptocurrency simulation game where you build and manage your own mining operation. Create your own coin, mine it, invest in other coins, upgrade and overclock GPUs or you can just HODL.

Revive & Prosper$19.99
A complex but not difficult voxel automation game with belts, trains, teleports, and even catapults for transport. Achieve efficiency through smart water control. Play with or without enemies. Produce materials and fuel for a spaceship. Deal with the toxic side effects. Can you Revive & Prosper?

The Final Earth 2$9.99
The Final Earth 2 is a vertical sci-fi city builder. Earth is unlivable, so you decide to create a space colony. Gather resources, then build and research your way to a better future! Grow your city from an exploration ship to a huge metropolis, full of advanced technology. What will you build?

Fate of the World$9.99
Fate of the World is a dramatic global strategy game that puts all our futures in your hands. The game features a dramatic set of scenarios based on the latest science covering the next two centuries. You must manage a balancing act of protecting the Earth’s resources and climate versus the needs of an ever-growing world population, who...

Let's School$19.99
Dive into the exhilarating role of a headmaster entrusted to revive your alma mater! Beyond just bricks and mortar, train teachers, recruit students. Sculpt your school into a unique educational haven! Let's School!

Your Island -KIMI NO SIMA-$12.99
Your people landed on a virgin forest island. Develop the island, build a house, make fields and barns, develop agriculture, fishery and industry, Let's develop into a wonderful island. It is a box-garden / sandbox-type simulation game that guides people and develops and develops islands. Andy maintenance (c)

Merge Me!$3.99
An idle merge game for your fun and relaxation. Combine various monsters, buy upgrades, unlock powerful artifacts and try to complete the game.

After the Collapse$14.99
ATC is a base building game set in a post-apocalyptic world featuring urban environments. Build a base across several layers with dozens of survivors. Fight other factions for the control of the remaining production centers and explore the world to find long forgotten resources and technologies.

Planetbase$14.99
Guide a group of space settlers trying to establish a base on a remote planet. Grow food, collect energy, mine resources, survive disasters and build a self-sufficient colony in a harsh and unforgiving environment.

Aven Colony$29.99
Build a new home for humanity in Aven Colony. Discover Aven Prime - an alien planet of deserts, tundras, and wetlands light years from earth. Build your colonies into massive, sprawling cities whilst dealing with the challenges faced when settling on a new world.

shapez$9.99
shapez is an easy-going, minimalistic factory building game about the automation of shapes through extraction and satisfying production lines. Adapt to increasingly complex shapes and grow your factory across an infinitely expanding map. Your only limitation is your creativity!

Idle Galaxy$1.99
Relaxing idle clicker game with various gameplay features. Challenging enough for hardcore players but it also can be fully completed.

Stable Orbit - Build your own space station$19.99
Design, build and control your own space station. Mission command and control is in your hands and only careful planning and vigilant supervision will keep your crew and space station safe.