Top similar games like Isolation:
Isolation FREE
The plague destroyed the world you once knew. This unknown bacteria destroyed the lives of many people who lived in various countries around the world. When the plague was first identified by doctors, researchers started working on a cure immediately. The infected people were transported into hospitals to isolate them from other people.
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Fear Protocol: Shadow ParadigmFREE
It's another nice dark day in Escondido, California and special agent Jack Banger goes from out of the frying pan and into the fire. The disgusting biomonster creatures are continuing to terrorize the city and there's only so much time before the plague spreads across the nation.

SCP: Hours to Go$1.99
SCP: Hours to Go is a survival horror escape room game based on the SCP Foundation Wiki. A catastrophic event shuts down the facility, leaving you alone in the security room. Solve puzzles and contain loose SCPs to escape, or survive for as long as possible for a high score.

Darkest Dungeon®$24.99
Darkest Dungeon is a challenging gothic roguelike turn-based RPG about the psychological stresses of adventuring. Recruit, train, and lead a team of flawed heroes against unimaginable horrors, stress, disease, and the ever-encroaching dark. Can you keep your heroes together when all hope is lost?

Holy Purge : Exorcist$9.99
Holy Purge is a co-op horror game where players play as priests who exorcise demons in various scenarios.

Temporal Purge: Z$4.99
Become an interdimensional zombie slayer in Temporal Purge: Z, an action-packed zombie-survival FPS. Face the zombie onslaught as you eradicate countless undead monsters on your quest to save the future.

Heralds of Silence. Chapter one$3.99
Heralds of Silence is a first-person horror game. Solve complex puzzles, look for clues, dive into the darkness of empty corridors and, perhaps, you will discover the secrets of a mysterious scientific complex and the curse of the Silence.

Abhorrent Light$4.99
A dark medieval first person hack and slash with procedural elements. Navigate the darkness and shed light on what lies below.

Dead Inside$4.99
A thrilling, first-person, action-survival game set in the modern post-apocalypse. As mankind’s last hope, you’ll traverse the hospital ravaged by a lethal plague. the fight for survival gets progressively more difficult as the story unfolds. Be ready for violence

Sword of the Stars: The Pit 2$14.99
The Pit2 returns to the turn-based Roguelike roots of the indie classic and takes you to another alien facility filled with broken machines, warped creatures, and new surprises!

Runt of the Litter$4.99
Steal and raise a baby war gryphon! Will you fight dragons together to save the empire, or defy the empire and lead your people to freedom?

Dehumanized$1.99
DeHumanized is a Roguelite sidescroller action shooter inspired by Metroid and Binding of Isaac.The world runs on physical rules with elements interacted subtly with each other. To survive you have to take strength from beasts, and learn rules how the world works.

Astrologaster$9.99
Astrologaster is a comedy game set in Shakespeare’s London. Play as 'Doctor' Simon Forman and treat his patients using astrology. A story-driven adventure based on a truly ridiculous story.

Plague M.D.$5.99
Plague M.D. is a medieval medicine simulator. Become a quack doctor stuck in a backwater village in the 16th century.

Unplagued$7.99
Play as plague doctors with your friends in this multiplayer co-op medieval horror! Purge the plague. Create the cure. Escape the mutated creatures. Make the queen proud.

Mask of the Plague Doctor$7.99
Stop a deadly plague in a medieval fantasy tale of swords and surgery! Unearth medical knowledge, prevent the town’s purge, or plot your own escape.

Pathologic Classic HD$12.99
Pathologic Classic HD is the Definitive Edition of the original Cult Classic Psychological First-Person Survival game. In this unforgettable experience, players control one of three unique characters as they try to save a mysterious town from a deadly plague that cannot be stopped.

Plague of Yamorn$5.99
Cleanse the infected in Plague of Yamorn, a 2D metroidvania. Explore the ruined town of Yamorn and uncover the secrets behind its downfall. Find and craft new equipment, offensive and defensive items. Exploit the plagues empowering properties to gain new powers and abilities.

Tales of the Black Death$9.99
An interactive story that pins your morality against your survival.

Plague Doctor: Contagion 430 BCE–2020 AD$2.99
Athens, 430 BCE. Marseille, 1720. Philadelphia, 1918. Louisville, 2020. Explore four cities—each battling a deadly epidemic—and make choices that will save or cost the lives of countless people. A first-person narrative adventure about greed, compassion, and courage in times of crisis.

AshenForest$6.99
AshenForest is a roguelite action RPG focused on boss-rush. To purify the ashen forest that is causing the plague, you must fight against all the monsters lurking in the forest.

Dark Ghost RPG$5.99
Together with the old prisoner, go on a hard and big trip to find the legendary land where there is no plague and darkness

Plague: London 1665$14.99
Plague: London 1665 is an RPG with pixel art graphics set in 1665's during the Bubonic Plague outbreak in overcrowded and polluted London. As a body collector, graveyard keeper, and family provider, avoid the disease while clearing the streets. Will you survive the outbreak or become another victim?

Caves of Plague$1.99
Strange and awful time has come when the plague swallowed the mankind. Horrific creatures left their graves, and evil spirits shrouded in the cities and countryside… Become a real guardian of retribution – a plague doctor! Explore the world of Caves of Plague!

SCP: ObserverFREE
SCP: Observer is a frightening experience in which you'll play the role of a maintenance engineer trapped inside a security room. Survive by managing the emergency power supply, monitoring the facility's camera system for threats and blocking the paths of oncoming horrors.

无梦少女 DreamlessGirl$6.99
Light up your fantasy with extra lives ✈︎ ⋆。˚A new type of bishoujo game combining "bullet hell shooting" and "visual novel."

Venice Bridges$4.99
Venice is under attack by malicious Plague Doctors and you have been chosen to come to its rescue. Plunge into the world of Venice Bridges, a 3D puzzle adventure game where the beauty of Venice meets hardship and destruction.

Kelipot$13.99
A mysterious plague befell ancient Celephais. What choices await the twins lost in the chaos? The Roguelite action-platformer Kelipot is here! With a rich story experience, frame-by-frame animations and hand-illustrated 2D visuals. Explore and uncover the truth beneath this twisted world!

Zombie Panic In Wonderland DX$9.99
The world of fairy tales has been overrun by a plague of bizarre zombies that wander along surrounded by a lovely yet pungent smell. Back to his hometown after a long time, Momotaro encounters these pests and finds himself forced to solve the issue.

Ahlman Mansion 2020FREE
Ahlman Mansion 2020 is a huge collection of games made by the Game Industry students at Ahlman Institute. Some content was created by Literature, Music and Art students. All games were made during our 10 month long school. The game developments ranged from 1 week to 2 and one took 5 weeks.

The Purification$0.99
As the last surviver you find yourself in a zombie infected wolrd. Survive by finding weapons and objects to escape the horror.

Penumbra: Black Plague Gold Edition$9.99
Surrounded by enemies and assaulted by terror from all sides, Philip must collect clues and solve vexing puzzles while combating the gnawing psychological terrors that assail his mind and threaten to strip him of his sanity.

Shovel Knight: Treasure Trove$39.99
Shovel Knight: Treasure Trove is the complete Shovel Knight collection, containing all 5 games in the epic saga! Dig, blast, slash, and bash your way through a fantastical, 8-bit inspired world of pixel-perfect platforming, memorable characters, and world-class action-adventure gameplay.

Woolfe - The Red Hood Diaries$9.99
Are you afraid of the big bad Woolfe? Step into the boots of a vengeful Red Riding Hood in this twisted-fairytale platformer. Defeat deranged fairytale bosses with your trusty axe, explore a gorgeous fantasy universe and piece together the truth behind the mysterious passing of Red’s father.

Boo Bunny Plague$1.99
Join Bunny and his pals Gunny, Faye, and Ganny on an epic quest to earn enough money to buy himself an Auto-repair unit!Boo Bunny Plague is an action/adventure game featuring a story with wacky musical cinematic scenes. The all original soundtrack has everything from punk rock to opera and feature musicians from Houston Texas.

The Curse of Nordic Cove$0.99
The Curse of the Nordic Cove is a game, by gamers, for gamers. There are familiar elements of gameplay for all gaming fans from First Person Shooter, Sports, Puzzle-Solving, to Driving, Strategic Shooting and Stealth and Dungeon Crawling.

MainlandFREE
A text adventure game about a 19th century explorer who finds himself stranded and alone.

Three Heroes$3.99
A magic world, epic heroes, bright graphics, excellent humor and absorbing gameplay – “Three Heroes”!

NightCry$24.99
NightCry is set on a cruise ship, and you have been invited along for the cruise of a (possibly short) lifetime. While your surroundings are luxurious and the guests are friendly, not everything is as it should be. The guests and the crew start to turn up dead, the victims of some foul murderer.

Rock-N-Rogue: A Boo Bunny Plague Adventure$1.99
Prepare for a dungeon crawl like you've never seen before. Choose from Bunny or one of his three inseparable pals, Gunny, Faye and Ganny, grab your instrument of choice, and battle your way to victory across nine hellish levels of undead creatures, demons and monsters. Level up your favorite character for more power than ever before!

Settled$0.99
Made in Construct2, Settled is a story driven game with hints of exploration. As you progress, subtle changes appear. Memories and nightmares act as new areas, although still remaining in the confines of the house. When you reach the end, the conclusion may not be what you expected.

Pathologic 2$34.99
Pathologic 2 is a groundbreaking open-world horror RPG. Resist the plague. Make medicine. Heal people. Perform an autopsy. Trade to get what you need. Fight and kill if necessary. Survive. Struggle with an outbreak in a secluded rural town that is rapidly turning into hell.

Plague Road$19.99
Rescue survivors, fight monsters and explore a once great city fallen to plague in a dark fantasy game combining turn-based tactical strategy and roguelike elements.

Malfunction$0.99
Malfunction is a puzzle/action game that aims to bring many unique ideas to the table. Malfunction's story evolves around a planet that is being overtaken by a fierce virus known as the 'Plague'. Your objective is to end this corruption from spreading furthermore.

Rusty Lake Paradise$3.99
Rusty Lake Paradise is set on a small remote island which is cursed by the ten plagues of Egypt. Solve all the mysteries of this dark, macabre puzzle adventure. Paradise builds upon the distinctive atmosphere and excitement from the Rusty Lake series.

DMD Mars Mission$4.99
The Martian mining facility FK16 has been invaded by insects and mutated creatures and now the system reports that all human workers have been killed. It's up to you and your assistant Isabel to save the situation.

Ye Fenny - Revenge of the Evil Good Shepherd$5.99
A top-down action adventure shooter, with a progressive story told through 90’s style cutscenes. Crisp graphics, crazy enemies, insane boss battles & that all-important 90’s style sound track to keep you pumped!

Undead Citadel$29.99
Exclusive for VR, UNDEAD CITADEL immerses you into an adventure encountering hundreds of Undead in breathtaking combats crammed with numerous foes. Slash, stab, crush, shoot or dismember with your own hands, as you find the way into the depths of the cursed citadel.

Doodle God: Genesis Secrets$11.99
If you loved the award winning Doodle God or any of the games in the Doodle series, you`ll have to try the new Doodle God Genesis Secrets. Players of all ages will enjoy a hidden object game mode with a unique Doodle God twist! Create an entire universe by mixing and matching different combinations.

We Happy Few - Soundtrack and Digital Goods Bundle$7.99
This Soundtrack and Digital Goods Bundle includes the official We Happy Few soundtrack in .MP3 and .FLAC format, along with other digital goodies to fill your life with Joy.

Ghosting Gun S$1.99
Fight the Plague with easy to learn controls and a linear game play focused on action in this 2D action game inspired by arcade games of old; Deal with enemies from a distance with your guns or get in close and personal with your blades, but mostly, combine them both to dominate the fight.

ADK$44.99
A.D.K is a third person horror title, with the mechanics of 90s classics. In addition to the various enemies, there will be puzzles, puzzles and many Ester Eggs.